Leith,
I have had the same issue with a Maico I used to own, although at the time didn't know of a cure and I always ran premium fuel thinking it was best.
The plug would fail after a couple of hours of use with no visible signs of carbon build up between the gap, it could be cleaned with some acetone and a good scrub and plug would be fine again. It turns out that there was a build up of carbon from the tip, over the insulator and back to the inside of the thread, this build up would allow the charge to run from the tip, over the insulator and earth out on the head, instead of its intended path from the tip across the gap.
This is what ktm are saying the problem is with the 65's and running the lower octane fuel fixed his problem instantly. The manual even states 95 octane fuel to be used.
I haven't had the problem with any other two strokes I've had running premium fuel, so I don't know what triggers it in different bikes, there was also someone else on the forum who had the same problem with a kx125.
Daggs,
So the jetting is standard, fuel/oil mix sounds about right and you foul 6 plugs in a day....sounds like a crank seal, does it blow a lot of smoke?