Yes. I'm running the Works Performance shock for the YZ400 D&E with an adjustable reservoir. (even with rez it weighs almost 3 lbs lighter than the stock shock.)
After I purchased it I ran across some negative comments about the shock on the internet. I had never ridden the bike with the shock when I took it out to race and was very apprehensive about riding it, but it ran great! (the thought of "yama-hop" already had me freaked out)
Right out of the box the bike had 2 1/2" of sag and ran well over small whoops and ruts, while bottoming softly over jumps. I was shocked (no pun intended) after having read the negative comments, but everyone's idea of a nice suspension is probably different.