Mark,
There's no question that if you want a FAST engine, the closer the ratios (eg YZ-A/B) the better. The simple reason is that when you change up it doesn't drop as low in rpm on a close ratio box so you are in a meatier part of the powerband. (Thats one major reason why YZA/Bs & VR Montesas are so fast.) But of course it requires a bit more tap-dancing on the shifter. (Hence my point about YZA/B ratios being a bit too close IMO, esp for a 360. Fine for Gary Jones back in the day, but for regular VMXers..?? Is it needed?)
A DT2M or MX-A gearset really needs a closer top gear for a fast engine, eg from YZ, as that std gap is really too big for a fast bike. Depending on the track, you may get away w gearing the bike to use 2nd to 5th, which means % drops of 24%, 21% & 14% (forgetting the 1-2 drop of 27%) w a YZ top gear. Not as fast as a full YZ gearset, but less tap-dancing
Using std DT/RT ratios, you'd also need a wider powerband & closer top gear, say from the DT2M, & likewise probably gear it to use 2nd to 5th, which means % drops of 27%, 23% & 21% (forgetting 1-2 drop of 29%) w the DT2M top gear (Only requires one gear changed IIRC). Still less fast than the above, but even less tap-dancing - a bit of a 'lazy-mans' race bike. With the right final drive ratio, you should be able to overcome Freaky's problem mentioned above (ie 1st too low; 2nd too hi) on his PP360 w this set-up.
Another important consideration is overall gear-ratio spread (bottom ratio divided by top ratio). You typically need about 2.2 - 2.3 in a 250 racebike; perhaps a little less for big-bore. (eg 4sp Maicos were 2.0 IIRC)